The effect of ultraviolet C radiation against different N95 respirators inoculated with SARS-CoV-2 Objectives: There are currently no studies that [...]
SARS-CoV-2 receptor networks in diabetic and COVID-19–associated kidney disease: COVID-19 morbidity and mortality are increased via unknown mechanisms in [...]
Compounds that exhibit assay interference or undesirable mechanisms of bioactivity (‘‘nuisance compounds’’) are routinely encountered in cellular assays, including [...]
Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2 This study is published in PNAS and details the role the Ace2 [...]
Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19 In this study, we used high content [...]
In a collaborative effort, the Sexton lab helped to quantitate cellular morphologies to establish that Hic-5 regulates vimentin organization [...]
Group photo of our High Content bootcamp in Utrecht, Netherlands.
High-Content Screening of Human Primary Muscle Satellite Cells for New Therapies for Muscular Atrophy/Dystrophy Results are encouraging [...]
Development of a Cell-Based Fluorescence Polarization Biosensor Using Preproinsulin to Identify Compounds That Alter Insulin Granule Dynamics [...]
N-substituted Phenylbenzamides of the Niclosamide chemotype attenuate obesity related changes in high fat diet fed mice Results [...]
