The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts
In a collaborative effort, the Sexton lab helped to quantitate cellular morphologies to establish that Hic-5 regulates vimentin organization [...]
December 2019
July 2019
#HCABootcamp in Utrecht
Group photo of our High Content bootcamp in Utrecht, Netherlands.
June 2018
High Content Screening – Human Muscle Stem Cells
High-Content Screening of Human Primary Muscle Satellite Cells for New Therapies for Muscular Atrophy/Dystrophy Results are encouraging [...]
Insulin FP Biosensor
Development of a Cell-Based Fluorescence Polarization Biosensor Using Preproinsulin to Identify Compounds That Alter Insulin Granule Dynamics [...]
Niclosamide and Analogs Improve Fatty Liver Disease
N-substituted Phenylbenzamides of the Niclosamide chemotype attenuate obesity related changes in high fat diet fed mice Results [...]
Non Alcoholic Fatty Liver Disease
NAFLD, an epidemic and a health disparity In association with the blanket term “metabolic syndrome” (which can be [...]